Justin Timberlake and Jessica Biel drifting apart?

The turbulent romance between Justin Timberlake and Jessica Biel seems to be well on course for the rocks.

Insiders say the pair, who’ve been dating two years, have had problems for ages, but when Justin was spotted allegedly cheating at New York’s upscale nightspot, ‘Avenue One,’ recently, it brought poor Ms Biel to a boil. “Things don’t look good for them right now â€" they’ve hit a really rocky spot,” a close friend of Justin told News reporters.

They have not been out in public from that day to this.

Things apparently started to go sour back in February, when JT and some buddies took a boy’s trip to Vegas. “Justin once had to leave dinner, because Jessica was calling incessantly,” says a friend. “They got into a huge screaming match on the phone about how she’s always checking on him. She’s extremely needy and is always keeping tabs on where JT is.”

That opinion seems shared by most of Justin’s close friends, “All his friends think she’s really annoying,” confirms another insider. “She’s always trying to be one of the guys. She and Justin have no chemistry.”

If your connection’s that brittle, it’s not smart to put a whole ocean between you â€" but that is exactly what’s Justin’s just done: He hopped on a plane and landed in London, where the 28-year old actor has been quite a cad; First, he attended the ‘White Tie and Tiara’ ball at Elton John’s mansion in Windsor, then a gig with Prince Harry in the verdant Hyde Park. Next stop was Wimbledon, then he debuted his clothes line, and then came a long night of parties with ex ‘Mr. Madonna,’ Guy Ritchie.

“Jessica wanted to go with him,” says the friend. “But he wasn’t having it. He just wanted to get away. He needed his space from her.”

You might think poor Jessie’s been dissed…and some say you’re right, “Jessica is really fun to be around,” says Justin’s former ’N-Sync’ band-mate, Lance Bass. “I haven’t spoken to Justin in a while, but the last I knew, he really loved her.”

In this crazy business, who can you believe? Even their own people were no help at all - Justin’s rep wouldn’t comment on his boss’s personal life, and Miss Jessica’s people didn’t even call back…So, you get to decide.